STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ntrCNitrogen metabolism transcriptional regulator, NtrC, Fis Family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (474 aa)    
Predicted Functional Partners:
Tola_0457
Signal transduction histidine kinase, nitrogen specific, NtrB; KEGG: aha:AHA_0275 nitrogen regulation protein NR(II); TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein.
 0.997
Tola_2938
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.805
Tola_0617
Multi-sensor hybrid histidine kinase; KEGG: aha:AHA_0905 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein.
  
 
 0.647
Tola_1628
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: pin:Ping_2985 fused histidine kinase sensor/response regulator.
 
 
 0.623
Tola_1388
Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; KEGG: mno:Mnod_4585 multi-sensor hybrid histidine kinase.
  
 
 0.610
Tola_2747
Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; histidine kinase HAMP region domain protein; KEGG: aha:AHA_0816 hybrid sensory histidine kinase BarA.
  
 
 0.610
Tola_1998
KEGG: glo:Glov_1989 multi-sensor hybrid histidine kinase; TIGRFAM: diguanylate cyclase; hemerythrin-like metal-binding protein; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; Hemerythrin HHE cation binding domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein.
  
 
 0.574
Tola_0458
KEGG: aha:AHA_0276 hypothetical protein.
       0.534
Tola_1314
Diguanylate cyclase with PAS/PAC and GAF sensors; KEGG: eca:ECA3270 hypothetical protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
 0.480
Tola_1953
Diguanylate cyclase with PAS/PAC and GAF sensors; KEGG: pfl:PFL_1403 sensory box-containing diguanylate cyclase, putative; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; GAF domain protein; PAS domain containing protein.
  
 
 0.480
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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