STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tola_0462PFAM: protein of unknown function DUF440; KEGG: aha:AHA_2131 dsDNA-mimic protein; Belongs to the UPF0263 family. (106 aa)    
Predicted Functional Partners:
Tola_1461
Chromosome segregation and condensation protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.761
Tola_1462
PFAM: chromosome segregation and condensation protein MukE; KEGG: aha:AHA_2378 condesin subunit E.
  
     0.760
Tola_1463
PFAM: chromosome segregation and condensation protein MukB domain protein; KEGG: aha:AHA_2377 cell division protein MukB.
  
     0.756
Tola_1120
PFAM: YfbU family protein; KEGG: aha:AHA_0893 hypothetical protein.
  
     0.748
Tola_1583
PFAM: protein of unknown function DUF331; KEGG: hap:HAPS_0665 hypothetical protein.
  
     0.738
seqA
SeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.729
Tola_3091
PFAM: amino acid-binding ACT domain protein; KEGG: kpn:KPN_04268 acetolactate synthase 2 regulatory subunit.
  
     0.724
Tola_2923
PFAM: protein of unknown function DUF1043; KEGG: aha:AHA_3907 hypothetical protein.
  
     0.719
Tola_0924
PFAM: protein of unknown function DUF1414; KEGG: kpe:KPK_1537 hypothetical protein; Belongs to the UPF0352 family.
  
     0.692
Tola_1132
KEGG: esa:ESA_01570 hypothetical protein.
  
     0.690
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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