| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Tola_0559 | Tola_0627 | Tola_0559 | Tola_0627 | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aha:AHA_3038 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.816 |
| Tola_0559 | Tola_0805 | Tola_0559 | Tola_0805 | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | KEGG: asa:ASA_0887 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | 0.903 |
| Tola_0559 | Tola_1379 | Tola_0559 | Tola_1379 | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | PFAM: aminotransferase class I and II; KEGG: aha:AHA_3110 putative aminotransferase B. | 0.806 |
| Tola_0559 | Tola_1546 | Tola_0559 | Tola_1546 | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: yen:YE1567 putative aminopeptidase N. | 0.916 |
| Tola_0559 | Tola_1853 | Tola_0559 | Tola_1853 | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | PFAM: aminotransferase class I and II; KEGG: cco:CCC13826_0327 aminotransferase, class II. | 0.806 |
| Tola_0559 | Tola_2013 | Tola_0559 | Tola_2013 | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | PepB aminopeptidase; PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: aha:AHA_1753 aminopeptidase B. | 0.914 |
| Tola_0559 | glyA | Tola_0559 | Tola_2527 | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.881 |
| Tola_0559 | gshA | Tola_0559 | Tola_0210 | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | KEGG: asa:ASA_0717 glutamate-cysteine ligase; TIGRFAM: glutamate/cysteine ligase; PFAM: glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | 0.913 |
| Tola_0559 | gshB | Tola_0559 | Tola_1250 | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | KEGG: asa:ASA_1197 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; glutathione synthetase domain protein; Belongs to the prokaryotic GSH synthase family. | 0.909 |
| Tola_0559 | pepA | Tola_0559 | Tola_0551 | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.914 |
| Tola_0627 | Tola_0559 | Tola_0627 | Tola_0559 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aha:AHA_3038 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | 0.816 |
| Tola_0627 | Tola_0805 | Tola_0627 | Tola_0805 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aha:AHA_3038 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | KEGG: asa:ASA_0887 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | 0.816 |
| Tola_0627 | Tola_1379 | Tola_0627 | Tola_1379 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aha:AHA_3038 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PFAM: aminotransferase class I and II; KEGG: aha:AHA_3110 putative aminotransferase B. | 0.914 |
| Tola_0627 | Tola_1546 | Tola_0627 | Tola_1546 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aha:AHA_3038 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: yen:YE1567 putative aminopeptidase N. | 0.857 |
| Tola_0627 | Tola_1853 | Tola_0627 | Tola_1853 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aha:AHA_3038 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PFAM: aminotransferase class I and II; KEGG: cco:CCC13826_0327 aminotransferase, class II. | 0.914 |
| Tola_0627 | Tola_2013 | Tola_0627 | Tola_2013 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aha:AHA_3038 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PepB aminopeptidase; PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: aha:AHA_1753 aminopeptidase B. | 0.831 |
| Tola_0627 | glyA | Tola_0627 | Tola_2527 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aha:AHA_3038 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.419 |
| Tola_0627 | gshA | Tola_0627 | Tola_0210 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aha:AHA_3038 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | KEGG: asa:ASA_0717 glutamate-cysteine ligase; TIGRFAM: glutamate/cysteine ligase; PFAM: glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | 0.833 |
| Tola_0627 | pepA | Tola_0627 | Tola_0551 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aha:AHA_3038 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.831 |
| Tola_0805 | Tola_0559 | Tola_0805 | Tola_0559 | KEGG: asa:ASA_0887 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | KEGG: ypy:YPK_3295 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein. | 0.903 |