STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tola_0796TIGRFAM: AmpG-related permease; PFAM: major facilitator superfamily MFS_1; KEGG: dar:Daro_0128 major facilitator transporter. (412 aa)    
Predicted Functional Partners:
menF
Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
  
  
 0.734
Tola_0795
PFAM: protein of unknown function DUF520; KEGG: asa:ASA_3207 nucleotide-binding protein; Belongs to the UPF0234 family.
       0.637
Tola_2586
N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: asa:ASA_0417 N-acetyl-anhydromuranmyl-L-alanine amidase.
 
   
 0.497
bamD
Outer membrane assembly lipoprotein YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.480
Tola_0793
TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: aha:AHA_1127 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme.
  
    0.467
Tola_0794
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
       0.467
nagZ
Glycoside hydrolase family 3 domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
 
   
 0.459
anmK
Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
  
   
 0.419
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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