STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tola_1318Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (783 aa)    
Predicted Functional Partners:
Tola_1996
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: aha:AHA_1497 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
    
 0.953
Tola_0401
TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: pyruvate carboxyltransferase; Conserved carboxylase region; biotin/lipoyl attachment domain-containing protein; KEGG: pmu:PM1422 pyruvate carboxylase subunit B.
  
 
 0.942
Tola_1848
TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; KEGG: pag:PLES_58301 putative transcarboxylase subunit.
  
 
 0.942
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
    
 0.922
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.916
Tola_1750
PFAM: Lactate/malate dehydrogenase; KEGG: aba:Acid345_1483 malate dehydrogenase (NAD); Belongs to the LDH/MDH superfamily.
  
 
 0.913
Tola_0213
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: sat:SYN_00517 NAD-dependent malic enzyme.
  
 
 0.912
Tola_0402
Sodium ion-translocating decarboxylase, beta subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family.
  
 
 0.912
Tola_0482
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: aha:AHA_4195 NADP-dependent malic enzyme.
  
 
 0.912
Tola_0881
KEGG: asa:ASA_2352 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical.
    
 0.912
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.