STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
mnmCtRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (636 aa)    
Predicted Functional Partners:
Tola_0317
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; KEGG: sfr:Sfri_0585 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.810
Tola_1105
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: sfr:Sfri_0585 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.810
Tola_2566
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pna:Pnap_2831 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.706
Tola_1573
PFAM: Beta-ketoacyl synthase; KEGG: asa:ASA_2365 3-oxoacyl-[acyl-carrier-protein] synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
 0.626
Tola_0560
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
  
 0.625
Tola_2726
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
  
 0.625
pdxB
D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
 
   
 0.619
Tola_3171
PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; major facilitator superfamily MFS_1; SMART: phospholipid/glycerol acyltransferase; KEGG: sde:Sde_3531 2-acyl-glycerophospho-ethanolamine acyltransferase.
  
  
 0.601
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.591
Tola_0968
PFAM: protein of unknown function DUF328; KEGG: ypb:YPTS_0629 hypothetical protein; Belongs to the UPF0246 family.
 
     0.567
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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