STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Tola_1802TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (233 aa)    
Predicted Functional Partners:
Tola_1800
PFAM: Biopolymer transport protein ExbD/TolR; KEGG: asa:ASA_1865 biopolymer transport protein ExbD/TolR.
 
 
 0.982
Tola_1801
PFAM: MotA/TolQ/ExbB proton channel; KEGG: tbd:Tbd_0712 MotA/TolQ/ExbB proton channel family protein.
 
 
 0.982
Tola_0678
PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: maq:Maqu_3532 TonB-dependent heme/hemoglobin receptor family protein.
  
 
 0.965
btuB
TonB-dependent receptor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
 
 
 
 0.934
tolR
Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.902
Tola_0056
KEGG: asa:ASA_1294 outer membrane lipoprotein.
    
   0.856
tolQ
Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.838
tolB
Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.686
Tola_0602
PFAM: MscS Mechanosensitive ion channel; KEGG: aha:AHA_3053 potassium efflux system KefA.
  
  
 0.637
Tola_1775
PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; molydopterin dinucleotide-binding region; KEGG: aha:AHA_3414 nitrate reductase.
   
  
 0.550
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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