STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tola_1950KEGG: asa:ASA_1094 hypothetical protein. (218 aa)    
Predicted Functional Partners:
Tola_1951
PFAM: AMP-dependent synthetase and ligase; KEGG: aha:AHA_3218 long-chain acyl-CoA synthetases.
   
 0.994
Tola_1952
KEGG: aha:AHA_3217 thermostable hemolysin.
 
   
 0.957
Tola_1949
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: asa:ASA_1093 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
   
 0.954
Tola_1948
KEGG: aha:AHA_3221 TPR repeat-containing protein.
 
     0.952
Tola_0217
TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: kpe:KPK_1619 phosphomethylpyrimidine kinase.
  
  
 0.840
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.624
Tola_1077
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: spq:SPAB_05151 sulfur carrier protein ThiS.
  
    0.564
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
  
  
 0.558
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.551
Tola_1076
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: yen:YE0291 thiamine biosynthesis protein.
  
  
 0.491
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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