STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tola_2022PFAM: Sterol-binding domain protein; KEGG: vvy:VV2689 putative lipid carrier protein. (174 aa)    
Predicted Functional Partners:
Tola_2024
PFAM: peptidase U32; KEGG: aha:AHA_1741 collagenase.
 
  
 0.964
Tola_2023
PFAM: peptidase U32; KEGG: asa:ASA_2617 putative protease.
 
  
 0.918
trmJ
RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
       0.645
Tola_0979
PFAM: DGC domain protein; KEGG: tmz:Tmz1t_0653 DGC domain protein.
 
    0.561
Tola_2073
PFAM: peptidase U32; KEGG: asa:ASA_3284 U32 family peptidase.
 
  
 0.558
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
       0.481
Tola_2020
Transcriptional regulator, BadM/Rrf2 family; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
       0.481
Tola_2018
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
       0.456
Tola_2810
PFAM: peptidase U32; KEGG: aha:AHA_1043 U32 family peptidase.
 
  
 0.440
Tola_2973
PFAM: protein of unknown function DUF1040; KEGG: aha:AHA_4219 hypothetical protein.
  
     0.422
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.