STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tola_2176PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: aha:AHA_2616 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (889 aa)    
Predicted Functional Partners:
Tola_1996
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: aha:AHA_1497 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 0.980
Tola_2876
TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: spe:Spro_1557 S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.979
Tola_2471
PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: pla:Plav_3451 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 0.966
Tola_0881
KEGG: asa:ASA_2352 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical.
 
 
 0.964
Tola_1902
Pyruvate formate-lyase; KEGG: kpe:KPK_3553 formate C-acetyltransferase 2; TIGRFAM: pyruvate formate-lyase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical.
 
 
 0.956
Tola_2307
Pyruvate formate-lyase; KEGG: yen:YE0646 putative formate acetyltransferase; TIGRFAM: pyruvate formate-lyase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical.
 
 
 0.956
Tola_0877
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.949
Tola_2575
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.943
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.940
Tola_2344
TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: kpe:KPK_1704 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 0.940
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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