STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tola_2184PFAM: peptidase M16 domain protein; KEGG: asa:ASA_1875 insulinase; Belongs to the peptidase M16 family. (929 aa)    
Predicted Functional Partners:
Tola_2183
TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: aha:AHA_1998 phosphohistidine phosphatase SixA.
 
     0.635
Tola_2925
KEGG: aha:AHA_3909 periplasmic serine peptidase DegS; TIGRFAM: periplasmic serine protease DegS; PFAM: PDZ/DHR/GLGF domain protein; peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein.
  
 
 0.526
Tola_2591
PFAM: protein of unknown function DUF416; KEGG: asa:ASA_0564 hypothetical protein.
  
     0.522
Tola_2822
PFAM: protein of unknown function DUF1451; KEGG: asa:ASA_1069 hypothetical protein.
  
     0.506
Tola_0760
KEGG: ppr:PBPRB0335 hypothetical protein.
  
     0.491
Tola_2549
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
   0.491
Tola_2525
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 
 0.484
Tola_2748
PFAM: phospholipid/glycerol acyltransferase; KEGG: asa:ASA_3551 hypothetical protein.
 
     0.470
Tola_2924
Protease Do; KEGG: aha:AHA_3908 serine peptidase DegQ; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family.
   
 
 0.463
Tola_2355
Sulfite reductase (NADPH) flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
   
 
  0.433
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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