| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Tola_2371 | apaH | Tola_2371 | Tola_2372 | PFAM: ApaG domain protein; KEGG: vvy:VV0477 ApaG. | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.899 |
| Tola_2371 | lptD | Tola_2371 | Tola_2367 | PFAM: ApaG domain protein; KEGG: vvy:VV0477 ApaG. | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.761 |
| Tola_2371 | pdxA | Tola_2371 | Tola_2369 | PFAM: ApaG domain protein; KEGG: vvy:VV0477 ApaG. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.821 |
| Tola_2371 | rsmA | Tola_2371 | Tola_2370 | PFAM: ApaG domain protein; KEGG: vvy:VV0477 ApaG. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.937 |
| Tola_2371 | surA | Tola_2371 | Tola_2368 | PFAM: ApaG domain protein; KEGG: vvy:VV0477 ApaG. | SurA domain protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.825 |
| Tola_3022 | apaH | Tola_3022 | Tola_2372 | PFAM: DSBA oxidoreductase; KEGG: aha:AHA_4216 thiol:disulfide interchange protein DsbA. | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.562 |
| Tola_3022 | bamA | Tola_3022 | Tola_2103 | PFAM: DSBA oxidoreductase; KEGG: aha:AHA_4216 thiol:disulfide interchange protein DsbA. | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.424 |
| Tola_3022 | bamB | Tola_3022 | Tola_0891 | PFAM: DSBA oxidoreductase; KEGG: aha:AHA_4216 thiol:disulfide interchange protein DsbA. | Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.535 |
| Tola_3022 | bamE | Tola_3022 | Tola_2261 | PFAM: DSBA oxidoreductase; KEGG: aha:AHA_4216 thiol:disulfide interchange protein DsbA. | SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.762 |
| Tola_3022 | ftsB | Tola_3022 | Tola_2741 | PFAM: DSBA oxidoreductase; KEGG: aha:AHA_4216 thiol:disulfide interchange protein DsbA. | Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.665 |
| Tola_3022 | lptD | Tola_3022 | Tola_2367 | PFAM: DSBA oxidoreductase; KEGG: aha:AHA_4216 thiol:disulfide interchange protein DsbA. | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.705 |
| Tola_3022 | surA | Tola_3022 | Tola_2368 | PFAM: DSBA oxidoreductase; KEGG: aha:AHA_4216 thiol:disulfide interchange protein DsbA. | SurA domain protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.687 |
| apaH | Tola_2371 | Tola_2372 | Tola_2371 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | PFAM: ApaG domain protein; KEGG: vvy:VV0477 ApaG. | 0.899 |
| apaH | Tola_3022 | Tola_2372 | Tola_3022 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | PFAM: DSBA oxidoreductase; KEGG: aha:AHA_4216 thiol:disulfide interchange protein DsbA. | 0.562 |
| apaH | ftsB | Tola_2372 | Tola_2741 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.528 |
| apaH | lptD | Tola_2372 | Tola_2367 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.721 |
| apaH | pdxA | Tola_2372 | Tola_2369 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.728 |
| apaH | rsmA | Tola_2372 | Tola_2370 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.831 |
| apaH | surA | Tola_2372 | Tola_2368 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | SurA domain protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.751 |
| bamA | Tola_3022 | Tola_2103 | Tola_3022 | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | PFAM: DSBA oxidoreductase; KEGG: aha:AHA_4216 thiol:disulfide interchange protein DsbA. | 0.424 |