node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tola_0471 | Tola_2388 | Tola_0471 | Tola_2388 | PFAM: Sporulation domain protein; KEGG: spe:Spro_4791 cell division protein FtsN. | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | 0.681 |
Tola_0505 | Tola_2388 | Tola_0505 | Tola_2388 | PFAM: Peptidase M23; KEGG: aha:AHA_0292 M23B family non-peptidase protein. | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | 0.672 |
Tola_0505 | Tola_2592 | Tola_0505 | Tola_2592 | PFAM: Peptidase M23; KEGG: aha:AHA_0292 M23B family non-peptidase protein. | PFAM: Peptidase M23; KEGG: aha:AHA_3724 metalloprotease opacity-associated protein A family. | 0.796 |
Tola_0505 | Tola_2735 | Tola_0505 | Tola_2735 | PFAM: Peptidase M23; KEGG: aha:AHA_0292 M23B family non-peptidase protein. | PFAM: Peptidase M23; Peptidoglycan-binding LysM; SMART: Peptidoglycan-binding LysM; KEGG: aha:AHA_0829 lipoprotein NlpD. | 0.416 |
Tola_2388 | Tola_0471 | Tola_2388 | Tola_0471 | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | PFAM: Sporulation domain protein; KEGG: spe:Spro_4791 cell division protein FtsN. | 0.681 |
Tola_2388 | Tola_0505 | Tola_2388 | Tola_0505 | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | PFAM: Peptidase M23; KEGG: aha:AHA_0292 M23B family non-peptidase protein. | 0.672 |
Tola_2388 | Tola_2389 | Tola_2388 | Tola_2389 | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | PFAM: protein of unknown function UPF0079; KEGG: asa:ASA_3373 hypothetical protein. | 0.872 |
Tola_2388 | Tola_2592 | Tola_2388 | Tola_2592 | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | PFAM: Peptidase M23; KEGG: aha:AHA_3724 metalloprotease opacity-associated protein A family. | 0.643 |
Tola_2388 | Tola_2735 | Tola_2388 | Tola_2735 | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | PFAM: Peptidase M23; Peptidoglycan-binding LysM; SMART: Peptidoglycan-binding LysM; KEGG: aha:AHA_0829 lipoprotein NlpD. | 0.654 |
Tola_2388 | hfq | Tola_2388 | Tola_2385 | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.674 |
Tola_2388 | miaA | Tola_2388 | Tola_2386 | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.879 |
Tola_2388 | mutL | Tola_2388 | Tola_2387 | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.882 |
Tola_2388 | nnrD | Tola_2388 | Tola_2390 | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.908 |
Tola_2388 | queG | Tola_2388 | Tola_2391 | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.632 |
Tola_2389 | Tola_2388 | Tola_2389 | Tola_2388 | PFAM: protein of unknown function UPF0079; KEGG: asa:ASA_3373 hypothetical protein. | KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM; SMART: cell wall hydrolase/autolysin; Peptidoglycan-binding LysM. | 0.872 |
Tola_2389 | hfq | Tola_2389 | Tola_2385 | PFAM: protein of unknown function UPF0079; KEGG: asa:ASA_3373 hypothetical protein. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.623 |
Tola_2389 | miaA | Tola_2389 | Tola_2386 | PFAM: protein of unknown function UPF0079; KEGG: asa:ASA_3373 hypothetical protein. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.896 |
Tola_2389 | mutL | Tola_2389 | Tola_2387 | PFAM: protein of unknown function UPF0079; KEGG: asa:ASA_3373 hypothetical protein. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.839 |
Tola_2389 | nnrD | Tola_2389 | Tola_2390 | PFAM: protein of unknown function UPF0079; KEGG: asa:ASA_3373 hypothetical protein. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.946 |
Tola_2389 | queG | Tola_2389 | Tola_2391 | PFAM: protein of unknown function UPF0079; KEGG: asa:ASA_3373 hypothetical protein. | Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.603 |