STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tola_2404KEGG: xca:xccb100_2412 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. (669 aa)    
Predicted Functional Partners:
Tola_2978
KEGG: aha:AHA_4129 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: HRDC domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: helicase domain protein; HRDC domain protein; DEAD-like helicase.
 
 0.989
Tola_1996
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: aha:AHA_1497 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
   0.986
Tola_2403
PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: bxe:Bxe_A1224 single-strand DNA-binding protein.
 
 
 0.981
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: aha:AHA_3247 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.946
Tola_0230
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 0.881
Tola_0487
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: dar:Daro_0217 glutamate synthase (NADH) large subunit.
  
  
 0.869
Tola_2398
KEGG: bpt:Bpet1291 hypothetical protein.
 
  
 0.859
Tola_2396
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: bpt:Bpet1290 hypothetical protein.
 
   
 0.858
Tola_2401
PFAM: Domain of unknown function DUF1845; KEGG: mpt:Mpe_A2339 hypothetical protein.
 
     0.849
Tola_2444
KEGG: ajs:Ajs_1398 hypothetical protein.
 
  
 0.845
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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