STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tola_2549Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. (329 aa)    
Predicted Functional Partners:
Tola_2552
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.984
Tola_2230
KEGG: aha:AHA_1922 type II citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.983
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.954
Tola_0401
TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: pyruvate carboxyltransferase; Conserved carboxylase region; biotin/lipoyl attachment domain-containing protein; KEGG: pmu:PM1422 pyruvate carboxylase subunit B.
    
 0.942
Tola_0413
KEGG: mag:amb3179 tartrate dehydratase subunit alpha; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region.
  
 
 0.942
Tola_0414
KEGG: bph:Bphy_5632 tartrate/fumarate subfamily Fe-S type hydro-lyase beta subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region.
  
 
 0.942
Tola_1848
TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; KEGG: pag:PLES_58301 putative transcarboxylase subunit.
    
 0.942
Tola_0213
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: sat:SYN_00517 NAD-dependent malic enzyme.
  
 0.926
Tola_0482
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: aha:AHA_4195 NADP-dependent malic enzyme.
  
 0.926
mqo
KEGG: maq:Maqu_3398 malate:quinone oxidoreductase; TIGRFAM: malate/quinone oxidoreductase; PFAM: Malate:quinone-oxidoreductase; FAD dependent oxidoreductase.
    
 0.921
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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