STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Experiments
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[Homology]
Score
Tola_2899KEGG: cja:CJA_2723 UreA amidolyase homolog; TIGRFAM: urea carboxylase; urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; Allophanate hydrolase subunit 1; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; SMART: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1. (1200 aa)    
Predicted Functional Partners:
Tola_2898
TIGRFAM: allophanate hydrolase; PFAM: Amidase; KEGG: tgr:Tgr7_3090 allophanate hydrolase.
  
 0.999
Tola_0401
TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: pyruvate carboxyltransferase; Conserved carboxylase region; biotin/lipoyl attachment domain-containing protein; KEGG: pmu:PM1422 pyruvate carboxylase subunit B.
 
 
 0.998
Tola_1848
TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; KEGG: pag:PLES_58301 putative transcarboxylase subunit.
 
 
0.998
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
  
 0.986
Tola_1860
PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: cti:RALTA_A0066 allophanate hydrolase subunit1 (AHS1).
  
 0.958
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
  
 0.948
Tola_1174
PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: ecf:ECH74115_3389 transcriptional regulator, IclR family, C-terminal domain.
  
    0.942
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
 0.942
Tola_3045
PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: kpe:KPK_1947 transcriptional regulator KdgR.
  
    0.942
Tola_1859
Urea amidolyase related protein; KEGG: kpn:KPN_00723 putative carboxylase; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2.
 
 
0.940
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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