STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tal-4Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa)    
Predicted Functional Partners:
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: aha:AHA_0154 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.942
Tola_0049
Ketose-bisphosphate aldolase; KEGG: ent:Ent638_0285 hypothetical protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
  
 
 0.929
Tola_1258
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.929
Tola_0407
TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: ecq:ECED1_1926 6-phosphofructokinase II; Belongs to the carbohydrate kinase PfkB family.
   
 
 0.924
fbp
Fructose-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: aha:AHA_2002 fructose-1,6-bisphosphatase.
  
 
 0.912
fbp-2
PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: aha:AHA_2002 fructose-1,6-bisphosphatase.
  
 
 0.912
Tola_0484
Fructose-1,6-bisphosphatase, class II; KEGG: aha:AHA_0464 fructose 1,6-bisphosphatase II; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein.
    
 0.910
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.910
Tola_2600
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
    
 0.908
Tola_3088
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.894
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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