STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAOG_0012356-pyruvoyl tetrahydrobiopterin synthase. (137 aa)    
Predicted Functional Partners:
CAOG_009136
GTP_cyclohydroI domain-containing protein.
  
 
 0.895
CAOG_002174
Sepiapterin reductase.
    
 0.862
CAOG_005867
NIF3-like protein 1; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
    
 0.775
CAOG_006287
Glycerophosphodiesterase GDE1.
   
  0.767
CAOG_004580
Short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.767
CAOG_005790
Uncharacterized protein.
   
  0.767
CAOG_002058
Aldehyde reductase.
    
 0.746
CAOG_007884
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.710
CAOG_004392
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
    
 0.627
CAOG_006957
Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
    
 0.627
Your Current Organism:
Capsaspora owczarzaki
NCBI taxonomy Id: 595528
Other names: C. owczarzaki ATCC 30864, Capsaspora owczarzaki ATCC 30864
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