STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAOG_0025812-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (478 aa)    
Predicted Functional Partners:
CAOG_007138
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
CAOG_000638
Branched chain keto acid dehydrogenase E1 beta polypeptide.
 0.999
CAOG_000368
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.988
CAOG_009572
Uncharacterized protein.
  
 0.963
CAOG_000413
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.963
CAOG_007095
Dihydrolipoyl dehydrogenase.
 
 
 0.949
CAOG_001722
Thioredoxin reductase 3.
  
 
 0.912
CAOG_001302
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 0.912
CAOG_004378
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.
  
 
 0.888
CAOG_005419
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.876
Your Current Organism:
Capsaspora owczarzaki
NCBI taxonomy Id: 595528
Other names: C. owczarzaki ATCC 30864, Capsaspora owczarzaki ATCC 30864
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