STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAOG_006251Hydroxymethylglutaryl-coenzyme A reductase. (841 aa)    
Predicted Functional Partners:
CAOG_001499
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.924
CAOG_000339
Mevalonate kinase.
  
 0.788
CAOG_001825
Insulin-induced 1 protein.
   
 
 0.716
CAOG_005518
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
  
 
 0.681
CAOG_007297
Squalene monooxygenase, variant 1.
   
  
 0.674
CAOG_005595
Cytochrome P450; Belongs to the cytochrome P450 family.
   
  
 0.644
CAOG_001935
Hydroxymethylglutaryl-CoA lyase.
    
 0.612
CAOG_004519
Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
    
 0.607
CAOG_008710
Uncharacterized protein.
    
 
 0.596
CAOG_003083
Synovial apoptosis inhibitor 1.
    
 
 0.596
Your Current Organism:
Capsaspora owczarzaki
NCBI taxonomy Id: 595528
Other names: C. owczarzaki ATCC 30864, Capsaspora owczarzaki ATCC 30864
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