STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAOG_007128Uncharacterized protein. (545 aa)    
Predicted Functional Partners:
CAOG_001989
DNA ligase.
   
 0.777
CAOG_000073
Macro domain-containing protein.
    
 
 0.774
CAOG_001703
DNA ligase III.
    
 
 0.774
CAOG_003706
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
    
 
 0.692
CAOG_004887
TOPEUc domain-containing protein.
    
 
 0.692
CAOG_001698
DNA ligase.
   
 
 0.687
CAOG_006357
ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.
    
 0.663
CAOG_003851
Zinc metalloproteinase.
    
 
 0.660
CAOG_005097
ATP-dependent DNA helicase II 70 kDa subunit.
     
 0.652
CAOG_003713
Uncharacterized protein.
    
 
 0.609
Your Current Organism:
Capsaspora owczarzaki
NCBI taxonomy Id: 595528
Other names: C. owczarzaki ATCC 30864, Capsaspora owczarzaki ATCC 30864
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.