STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU34396.1KEGG: vap:Vapar_0149 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. (402 aa)    
Predicted Functional Partners:
ADU39008.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mno:Mnod_3128 pyridoxal-5'-phosphate-dependent protein beta subunit.
 
 
0.949
ADU36301.1
TIGRFAM: threonine synthase; KEGG: vap:Vapar_1832 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit.
  
 
 0.944
ADU34852.1
KEGG: vap:Vapar_0576 threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase.
  
 
 0.936
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.935
leuB-2
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.935
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.933
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.927
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 
 0.917
ADU37347.1
PFAM: aminotransferase class V; KEGG: vap:Vapar_2906 aminotransferase class V.
  
 0.916
ADU39011.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: vap:Vapar_4235 pyridoxal-5'-phosphate-dependent protein beta subunit.
  
 
 0.908
Your Current Organism:
Variovorax paradoxus EPS
NCBI taxonomy Id: 595537
Other names: V. paradoxus EPS, Variovorax paradoxus str. EPS, Variovorax paradoxus strain EPS
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.