STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU34931.1KEGG: vap:Vapar_3058 prolyl aminopeptidase; PFAM: alpha/beta hydrolase fold. (309 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
  0.901
ADU35319.1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
  0.900
ADU35619.1
Procollagen-proline dioxygenase; PFAM: 2OG-Fe(II) oxygenase; KEGG: vap:Vapar_1302 procollagen-proline dioxygenase; SMART: Prolyl 4-hydroxylase alpha subunit.
     
  0.900
ADU38711.1
Procollagen-proline dioxygenase; PFAM: 2OG-Fe(II) oxygenase; KEGG: vap:Vapar_3584 procollagen-proline dioxygenase; SMART: Prolyl 4-hydroxylase alpha subunit.
     
  0.900
ADU39485.1
KEGG: vap:Vapar_4693 ornithine cyclodeaminase; PFAM: ornithine cyclodeaminase/mu-crystallin.
     
  0.900
ADU34929.1
KEGG: mpt:Mpe_A2587 pyrroloquinoline quinone biosynthesis protein D.
 
     0.801
pqqB
Coenzyme PQQ biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
 
     0.791
pqqC
Coenzyme PQQ biosynthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
 
     0.789
pqqE
Coenzyme PQQ biosynthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
       0.758
pqqA
Coenzyme PQQ biosynthesis protein A; Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide; Belongs to the PqqA family.
       0.588
Your Current Organism:
Variovorax paradoxus EPS
NCBI taxonomy Id: 595537
Other names: V. paradoxus EPS, Variovorax paradoxus str. EPS, Variovorax paradoxus strain EPS
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