STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU35225.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)    
Predicted Functional Partners:
ADU35224.1
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.999
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 0.994
accA
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 0.993
ADU35742.1
Manually curated; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; KEGG: vap:Vapar_1390 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase.
 
 
 0.972
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.966
ADU40080.1
KEGG: vap:Vapar_5200 biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase.
 
 0.947
ADU36437.1
PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; KEGG: vap:Vapar_3389 3-oxoacyl-(acyl carrier protein) synthase III.
  
 
 0.929
ADU36729.1
PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; KEGG: vap:Vapar_2349 3-oxoacyl-(acyl carrier protein) synthase III.
  
 
 0.929
ADU34919.1
PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; KEGG: dac:Daci_5726 carbamoyl-phosphate synthase L chain ATP-binding.
 
 
0.923
ADU36656.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; KEGG: vap:Vapar_5478 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
  0.916
Your Current Organism:
Variovorax paradoxus EPS
NCBI taxonomy Id: 595537
Other names: V. paradoxus EPS, Variovorax paradoxus str. EPS, Variovorax paradoxus strain EPS
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.