STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU35726.1PFAM: protein of unknown function DUF513 hemX; KEGG: vap:Vapar_1376 protein of unknown function DUF513 HemX. (366 aa)    
Predicted Functional Partners:
ADU35725.1
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 0.994
ADU35727.1
PFAM: HemY domain protein; KEGG: vap:Vapar_1377 HemY domain protein.
  
 0.984
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 
 0.975
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.944
ADU38220.1
KEGG: vap:Vapar_3532 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.939
ADU39759.1
Porphobilinogen synthase; Manually curated; KEGG: vap:Vapar_4926 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 
 0.800
ADU35212.1
PFAM: ribonuclease II; KEGG: vap:Vapar_0937 ribonuclease II.
  
     0.762
ADU34868.1
Hypothetical protein; KEGG: vap:Vapar_0592 putative proline rich signal peptide protein.
  
     0.751
ADU35263.1
KEGG: vap:Vapar_0981 hypothetical protein.
 
  
 0.734
ADU38958.1
KEGG: vap:Vapar_4127 hypothetical protein.
  
    0.730
Your Current Organism:
Variovorax paradoxus EPS
NCBI taxonomy Id: 595537
Other names: V. paradoxus EPS, Variovorax paradoxus str. EPS, Variovorax paradoxus strain EPS
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.