STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU36446.1KEGG: vap:Vapar_3380 lytic murein transglycosylase B; manually curated; TIGRFAM: lytic murein transglycosylase B. (366 aa)    
Predicted Functional Partners:
ADU36445.1
KEGG: vap:Vapar_3381 hypothetical protein.
       0.785
ADU36447.1
KEGG: vap:Vapar_3379 transglutaminase domain protein; PFAM: transglutaminase domain-containing protein; SMART: transglutaminase domain-containing protein.
       0.766
lptD
Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
     0.587
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
     0.574
ADU38548.1
KEGG: vap:Vapar_3793 aminopeptidase N; TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase.
  
   
 0.502
ADU36713.1
PFAM: Lytic transglycosylase catalytic; MLTD_N domain protein; Peptidoglycan-binding lysin domain; KEGG: vap:Vapar_2337 lytic transglycosylase catalytic.
  
   
 0.491
surA
SurA domain; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
 
   
 0.428
bamE
SmpA/OmlA domain-containing protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
  
 0.426
ADU36448.1
PFAM: protein of unknown function DUF58; KEGG: vap:Vapar_3378 protein of unknown function DUF58.
       0.424
ftsB
Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
 
     0.415
Your Current Organism:
Variovorax paradoxus EPS
NCBI taxonomy Id: 595537
Other names: V. paradoxus EPS, Variovorax paradoxus str. EPS, Variovorax paradoxus strain EPS
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