STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU37032.1PFAM: ATP dependent DNA ligase; KEGG: vap:Vapar_2739 DNA ligase. (284 aa)    
Predicted Functional Partners:
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
    
 0.911
ADU39653.1
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: vap:Vapar_4859 ATP-dependent DNA ligase.
     
  0.900
ADU34225.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.810
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.784
ADU37033.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: vap:Vapar_2740 short-chain dehydrogenase/reductase SDR.
       0.615
ADU39275.1
KEGG: vap:Vapar_6015 DNA polymerase II; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B.
   
 0.564
ADU37289.1
KEGG: vap:Vapar_2857 DNA-directed DNA polymerase.
   
 0.551
ADU39109.1
PFAM: metallophosphoesterase; KEGG: bbt:BBta_4590 putative modular protein.
 
 0.506
ADU37034.1
PFAM: extracellular solute-binding protein family 5; KEGG: aav:Aave_3254 extracellular solute-binding protein.
       0.457
ADU39546.1
TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: vap:Vapar_4742 histidinol-phosphate phosphatase family protein.
   
 0.442
Your Current Organism:
Variovorax paradoxus EPS
NCBI taxonomy Id: 595537
Other names: V. paradoxus EPS, Variovorax paradoxus str. EPS, Variovorax paradoxus strain EPS
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.