STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU38336.1PFAM: restriction endonuclease; DNA topoisomerase type IA zn finger domain protein; KEGG: rfr:Rfer_1819 restriction endonuclease. (318 aa)    
Predicted Functional Partners:
ADU37803.1
KEGG: vap:Vapar_4061 4Fe-4S ferredoxin iron-sulfur binding domain protein.
   
    0.882
ADU38567.1
KEGG: vap:Vapar_3814 4Fe-4S ferredoxin iron-sulfur binding domain protein.
   
    0.882
ADU37828.1
KEGG: rpf:Rpic12D_3972 AcnD-accessory protein PrpF; TIGRFAM: AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453.
   
  
 0.767
ADU34620.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 0.756
ADU38337.1
KEGG: xac:XAC3658 hypothetical protein.
       0.737
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.670
leuS
KEGG: vap:Vapar_0422 leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.640
ADU38335.1
PFAM: Peptidase M23; KEGG: vap:Vapar_3617 peptidase M23.
       0.570
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.542
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
   
 
 0.519
Your Current Organism:
Variovorax paradoxus EPS
NCBI taxonomy Id: 595537
Other names: V. paradoxus EPS, Variovorax paradoxus str. EPS, Variovorax paradoxus strain EPS
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