STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (303 aa)    
Predicted Functional Partners:
nadE-2
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.943
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.936
ADU39833.1
Cytidyltransferase-related domain protein; KEGG: bvi:Bcep1808_5372 bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase; TIGRFAM: cytidyltransferase-related domain protein; PFAM: NUDIX hydrolase; cytidylyltransferase.
    
 0.925
ADU34526.1
PFAM: Silent information regulator protein Sir2; KEGG: vap:Vapar_0294 silent information regulator protein Sir2.
  
 
 0.924
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.922
ADU34640.1
KEGG: vap:Vapar_6043 NAD(P) transhydrogenase, subunit alpha part 2.
     
 0.917
ADU34639.1
KEGG: vap:Vapar_6044 NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein.
     
 0.916
ADU34641.1
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.910
ADU39150.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
  
 0.905
ADU35614.1
PFAM: NUDIX hydrolase; KEGG: vap:Vapar_1297 NUDIX hydrolase.
     
 0.904
Your Current Organism:
Variovorax paradoxus EPS
NCBI taxonomy Id: 595537
Other names: V. paradoxus EPS, Variovorax paradoxus str. EPS, Variovorax paradoxus strain EPS
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