STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL50943.1PFAM: pentapeptide repeat protein; KEGG: dsa:Desal_3343 pentapeptide repeat protein. (194 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.816
EFL52606.1
Serine/threonine protein kinase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Serine/threonine-protein kinase-like domain; GAF domain protein; KEGG: ava:Ava_2803 serine/threonine protein kinase and signal transduction histidine kinase (STHK) with GAF sensor; SMART: GGDEF domain containing protein; serine/threonine protein kinase; GAF domain protein.
 
 
 0.805
EFL52885.1
KEGG: dma:DMR_05480 hypothetical protein; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
   
 
 0.665
EFL49255.1
KEGG: dma:DMR_39000 putative transglycosylase; PFAM: Lytic transglycosylase catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
   
 
 0.662
EFL50041.1
PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; KEGG: dma:DMR_38840 putative sensor histidine kinase; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; PAS domain containing protein; histidine kinase A domain protein.
   
 0.589
EFL50575.1
TIGRFAM: pyruvate kinase; KEGG: dma:DMR_05180 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
    
 0.583
EFL50001.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; KEGG: dma:DMR_37680 two-component hybrid sensor and regulator; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein.
   
 0.577
EFL51763.1
TIGRFAM: PAS sensor protein; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; KEGG: dma:DMR_10940 sensor histidine kinase; SMART: PAS domain containing protein; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein.
    
 0.524
EFL52270.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: dma:DMR_28760 putative sensor histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
     
 0.508
EFL52740.1
PFAM: OmpA/MotB domain protein; KEGG: dma:DMR_43090 putative outer membrane protein.
 
 
 0.500
Your Current Organism:
Desulfovibrio fructosivorans
NCBI taxonomy Id: 596151
Other names: D. fructosivorans JJ, Desulfovibrio fructosivorans ATCC 49200, Desulfovibrio fructosivorans DSM 3604, Desulfovibrio fructosivorans JJ, Desulfovibrio fructosivorans str. JJ, Desulfovibrio fructosivorans strain JJ, Desulfovibrio fructosovorans JJ
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