STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL50313.1KEGG: dma:DMR_31790 glycine dehydrogenase [decarboxylating] subunit 2. (482 aa)    
Predicted Functional Partners:
EFL51819.1
Glycine cleavage system T protein; KEGG: dma:DMR_18240 aminomethyltransferase; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel.
 0.999
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.999
gcvPA
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
0.999
EFL50314.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: dma:DMR_31800 putative dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 0.966
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.960
EFL52138.1
PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; KEGG: dma:DMR_18800 succinyl-CoA synthetase beta chain/succinyl-CoA synthetase alpha chain.
  
  
 0.883
purD
TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: dma:DMR_16750 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family.
   
  
 0.857
EFL49569.1
KEGG: dma:DMR_28220 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase.
   
  
 0.821
EFL51682.1
PFAM: ferredoxin-dependent glutamate synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dma:DMR_46030 glutamate synthase large subunit; Belongs to the glutamate synthase family.
   
 0.765
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
  
 0.759
Your Current Organism:
Desulfovibrio fructosivorans
NCBI taxonomy Id: 596151
Other names: D. fructosivorans JJ, Desulfovibrio fructosivorans ATCC 49200, Desulfovibrio fructosivorans DSM 3604, Desulfovibrio fructosivorans JJ, Desulfovibrio fructosivorans str. JJ, Desulfovibrio fructosivorans strain JJ, Desulfovibrio fructosovorans JJ
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