STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL49491.1PFAM: alpha/beta hydrolase fold; KEGG: dma:DMR_44780 hypothetical protein. (274 aa)    
Predicted Functional Partners:
EFL49492.1
TIGRFAM: modD protein; KEGG: glo:Glov_0448 ModD protein; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
    
  0.759
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.703
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
    
  0.690
EFL51208.1
PFAM: glutamine amidotransferase class-I; coagulation factor 5/8 type domain protein; KEGG: fre:Franean1_5989 GMP synthase.
    
  0.690
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
  0.684
EFL50619.1
PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; [2Fe-2S]-binding domain protein; ferredoxin; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: dma:DMR_05980 aldehyde oxidoreductase.
     
 0.684
EFL49606.1
PFAM: CinA domain protein; KEGG: dma:DMR_03760 hypothetical protein; Belongs to the CinA family.
  
 
  0.647
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
    
  0.623
EFL52607.1
PFAM: Inosine/uridine-preferring nucleoside hydrolase; Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pin:Ping_1902 inosine/uridine-preferring nucleoside hydrolase.
    
  0.623
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
  0.623
Your Current Organism:
Desulfovibrio fructosivorans
NCBI taxonomy Id: 596151
Other names: D. fructosivorans JJ, Desulfovibrio fructosivorans ATCC 49200, Desulfovibrio fructosivorans DSM 3604, Desulfovibrio fructosivorans JJ, Desulfovibrio fructosivorans str. JJ, Desulfovibrio fructosivorans strain JJ, Desulfovibrio fructosovorans JJ
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