STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIG53426.1PFAM: Protein of unknown function (DUF3431). (218 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.773
EIG53425.1
K+ transport system, NAD-binding component; PFAM: TrkA-N domain; Ion channel; TrkA-C domain.
       0.773
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
       0.741
EIG55258.1
Protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase.
  
     0.689
EIG54013.1
Hypothetical protein.
  
     0.609
EIG53423.1
Hypothetical protein.
       0.545
EIG53760.1
Phosphoenolpyruvate carboxykinase (ATP).
  
     0.477
EIG55520.1
PFAM: Histidine kinase; 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
     0.450
EIG55369.1
PFAM: AIPR protein.
  
     0.427
EIG53422.1
TIGR00730 family protein; PFAM: Possible lysine decarboxylase; Belongs to the LOG family.
       0.424
Your Current Organism:
Desulfovibrio sp. U5L
NCBI taxonomy Id: 596152
Other names: D. sp. U5L
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.