Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (397 aa)    
Predicted Functional Partners:
EIG54843.1
PFAM: Methionine biosynthesis protein MetW; TIGRFAM: methionine biosynthesis protein MetW.
   
 0.995
EIG54547.1
OAH/OAS sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
 
 
 0.984
EIG53215.1
PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase.
  
 
 0.972
EIG53188.1
PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase; ACT domain.
 
 
 0.927
EIG54382.1
Threonine dehydratase, medium form; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.885
EIG53344.1
Aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; Belongs to the aspartokinase family.
   
 0.876
EIG55626.1
Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme.
    
 0.852
EIG55094.1
Phosphoserine phosphatase SerB; PFAM: ACT domain; haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB.
     
 0.851
glyA
Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.849
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.826
Your Current Organism:
Desulfovibrio sp. U5L
NCBI taxonomy Id: 596152
Other names: D. sp. U5L
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