Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rsmGMethyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (215 aa)    
Predicted Functional Partners:
mnmG
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
 
  
 0.988
mnmE
tRNA modification GTPase mnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
  
 0.937
AEB82497.1
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: dia:Dtpsy_0048 cobyrinic acid ac-diamide synthase.
  
  
 0.850
AEB82499.1
TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KEGG: aav:Aave_0056 chromosome segregation DNA-binding protein; SMART: ParB-like nuclease; Belongs to the ParB family.
  
  
 0.822
AEB82494.1
KEGG: pct:PC1_0787 hypothetical protein.
       0.773
AEB82496.1
PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: dia:Dtpsy_0047 lysine exporter protein (LysE/YggA).
       0.720
der
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
   
 0.656
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
   
 0.653
yidC
Membrane protein insertase, YidC/Oxa1 family domain containing; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
  
 0.641
AEB82491.1
Protein of unknown function UPF0153; PFAM: Uncharacterised protein family UPF0153; KEGG: dia:Dtpsy_0043 protein of unknown function UPF0153.
       0.625
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (18%) [HD]