Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB82519.1KEGG: ajs:Ajs_0052 hypothetical protein; TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6; PFAM: Monooxygenase, FAD-binding. (422 aa)    
Predicted Functional Partners:
ubiG
Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 0.906
ubiA
4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
  
  
 0.839
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
  
 
 0.677
coq7
Putative ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
   
 0.671
ubiB
2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
  
 0.616
AEB85071.1
ABC-1 domain-containing protein; PFAM: ABC-1; KEGG: ajs:Ajs_2681 2-octaprenylphenol hydroxylase.
  
 0.614
AEB83716.1
UbiD family decarboxylase; KEGG: ajs:Ajs_3225 3-octaprenyl-4hydroxybenzoate decarboxylase; TIGRFAM: Carboxylyase-related; PFAM: Carboxylyase-related; Belongs to the UbiD family.
    
 0.585
AEB83715.1
PFAM: Cytochrome P450; KEGG: ajs:Ajs_3226 cytochrome P450.
  
 
 0.567
AEB83045.1
PFAM: Methyltransferase type 11; KEGG: azl:AZL_f01750 hypothetical protein.
  
 0.564
AEB82520.1
TIGRFAM: Acetoacetyl-CoA synthase; KEGG: dia:Dtpsy_0074 acetoacetyl-CoA synthetase; PFAM: AMP-dependent synthetase/ligase.
  
  
 0.556
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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