Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AEB82537.1PFAM: UspA; KEGG: ajs:Ajs_0074 UspA domain-containing protein. (140 aa)    
Predicted Functional Partners:
AEB83522.1
PFAM: UspA; KEGG: dia:Dtpsy_0997 UspA domain protein.
 
     0.757
AEB86595.1
PFAM: UspA; KEGG: dia:Dtpsy_3142 UspA domain protein.
  
     0.692
AEB82538.1
Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: ajs:Ajs_0075 metallophosphoesterase.
       0.660
AEB82539.1
PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; KEGG: ajs:Ajs_0076 LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.492
AEB84038.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
    0.418
AEB83546.1
methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.413
AEB85264.1
methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.413
AEB82770.1
PFAM: Mg2+ transporter protein, CorA-like; KEGG: dia:Dtpsy_0260 Mg2 transporter protein CorA family protein.
 
  
 0.412
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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