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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB82649.1KEGG: aav:Aave_0233 nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein PII; SMART: Nitrogen regulatory protein PII; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
AEB82650.1
KEGG: ajs:Ajs_0164 ammonium transporter; TIGRFAM: Ammonium transporter; PFAM: Ammonium transporter.
 
 0.999
glnD
UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
 
 
 0.801
AEB82648.1
KEGG: dia:Dtpsy_0180 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP02001; PFAM: Conserved hypothetical protein CHP02001.
  
    0.799
AEB83832.1
Manually curated; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; KEGG: dia:Dtpsy_1111 signal transduction histidine kinase, nitrogen specific, NtrB; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
  
 
 0.762
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 
 
 0.745
argA
Amino-acid N-acetyltransferase; KEGG: ajs:Ajs_2327 N-acetylglutamate synthase; TIGRFAM: Amino-acid N-acetyltransferase (ArgA); PFAM: Aspartate/glutamate/uridylate kinase; GCN5-related N-acetyltransferase (GNAT) domain; Belongs to the acetyltransferase family. ArgA subfamily.
   
 
 0.711
AEB83253.1
KEGG: ajs:Ajs_0769 putative transmembrane protein.
    
 
 0.686
AEB83359.1
PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; KEGG: ajs:Ajs_0898 TPR repeat-containing protein.
    
 
 0.686
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
  
   
 0.673
flhC
Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.
      
 0.627
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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