STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (312 aa)    
Predicted Functional Partners:
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 0.981
ilvD
TIGRFAM: Dihydroxy-acid dehydratase; KEGG: dia:Dtpsy_0987 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 0.977
ilvD-2
TIGRFAM: Dihydroxy-acid dehydratase; KEGG: dia:Dtpsy_0988 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 0.977
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.977
AEB83010.1
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; KEGG: pol:Bpro_0274 branched-chain alpha-keto acid dehydrogenase E1 component; SMART: Transketolase-like, pyrimidine-binding domain.
  
 0.932
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.921
AEB83009.1
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); KEGG: pol:Bpro_0273 branched-chain alpha-keto acid dehydrogenase E1 component; PFAM: Dehydrogenase, E1 component; 2-oxoisovalerate dehydrogenase, E1 alpha subunit, N-terminal.
  
 
 0.917
AEB83578.1
Aspartate transaminase; KEGG: dia:Dtpsy_2560 aminotransferase AlaT; PFAM: Aminotransferase, class I/classII.
  
 
 0.914
AEB86758.1
KEGG: dia:Dtpsy_3259 glutamate/cysteine ligase; TIGRFAM: Glutamate--cysteine ligase GshA; PFAM: Glutamate--cysteine ligase GshA.
   
 
 0.906
gshA
TIGRFAM: Glutamate--cysteine ligase, monofunctional; KEGG: dia:Dtpsy_1339 glutamate/cysteine ligase; PFAM: Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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