STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB82693.1Cupin 2 conserved barrel domain protein; KEGG: dia:Dtpsy_0215 transcriptional regulator, AraC family; PFAM: Cupin 2, conserved barrel; SMART: Helix-turn-helix, AraC type, DNA binding domain. (221 aa)    
Predicted Functional Partners:
AEB86544.1
KEGG: dia:Dtpsy_3105 flagellar basal-body rod protein FlgG; TIGRFAM: Flagellar basal-body rod FlgG; Fagellar hook-basal body protein, FlgE/F/G; PFAM: Domain of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; Belongs to the flagella basal body rod proteins family.
    
   0.705
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.679
rpoH
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
   
 
 0.679
AEB82694.1
Protein of unknown function DUF6 transmembrane; PFAM: Drug/metabolite transporter; KEGG: ajs:Ajs_0201 hypothetical protein.
 
  
 0.678
AEB82692.1
PFAM: Major facilitator superfamily MFS-1; KEGG: dia:Dtpsy_0214 major facilitator superfamily MFS_1.
     
 0.606
cobB
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
  
  
 0.554
cobB-2
NAD-dependent deacetylase; KEGG: dia:Dtpsy_1612 silent information regulator protein Sir2; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; Belongs to the sirtuin family. Class III subfamily.
  
  
 0.554
AEB82695.1
PFAM: Peptidase M48; KEGG: ajs:Ajs_0203 peptidase M48, Ste24p.
     
 0.537
AEB83104.1
TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: rfr:Rfer_0711 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.535
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.530
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.