Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEB82695.1PFAM: Peptidase M48; KEGG: ajs:Ajs_0203 peptidase M48, Ste24p. (284 aa)    
Predicted Functional Partners:
AEB82694.1
Protein of unknown function DUF6 transmembrane; PFAM: Drug/metabolite transporter; KEGG: ajs:Ajs_0201 hypothetical protein.
       0.781
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
    0.706
AEB82693.1
Cupin 2 conserved barrel domain protein; KEGG: dia:Dtpsy_0215 transcriptional regulator, AraC family; PFAM: Cupin 2, conserved barrel; SMART: Helix-turn-helix, AraC type, DNA binding domain.
  
  
 0.545
AEB84310.1
TniQ family protein; KEGG: bxe:Bxe_C1175 transposition protein TniQ; manually curated; PFAM: TniQ.
   
 
 0.510
AEB82692.1
PFAM: Major facilitator superfamily MFS-1; KEGG: dia:Dtpsy_0214 major facilitator superfamily MFS_1.
       0.493
AEB83359.1
PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; KEGG: ajs:Ajs_0898 TPR repeat-containing protein.
   
 
 0.482
AEB83404.1
Carboxyl-terminal protease; TIGRFAM: Peptidase S41A, C-terminal peptidase; PFAM: Peptidase S41; PDZ/DHR/GLGF; KEGG: ajs:Ajs_3506 C-terminal processing peptidase-3; SMART: Peptidase S41; PDZ/DHR/GLGF; Belongs to the peptidase S41A family.
  
 
 0.468
AEB83255.1
KEGG: ajs:Ajs_0771 putative lipoprotein.
   
 
 0.463
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.420
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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