STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB82712.14-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (345 aa)    
Predicted Functional Partners:
AEB82711.1
Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
 0.998
AEB82710.1
TIGRFAM: 2-oxopent-4-enoate hydratase; KEGG: ajs:Ajs_0222 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetase, C-terminal-like.
 
 
 0.994
AEB85547.1
Fumarylacetoacetate (FAA) hydrolase; PFAM: Fumarylacetoacetase, C-terminal-like; KEGG: ajs:Ajs_1712 hydratase/decarboxylase.
 
 
 0.979
AEB82709.1
KEGG: ctt:CtCNB1_3150 alpha/beta hydrolase fold protein; PFAM: Alpha/beta hydrolase fold-1.
 
 
 0.943
AEB82713.1
TIGRFAM: 4-oxalocrotonate decarboxylase; KEGG: ajs:Ajs_0225 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetase, C-terminal-like.
 
  
 0.941
AEB82761.1
Aconitate hydratase domain-containing protein; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; KEGG: cti:RALTA_B0856 putative hydrolyase.
  
  
 0.859
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.800
AEB82705.1
TIGRFAM: Catechol 2,3 dioxygenase; KEGG: ajs:Ajs_0218 catechol 2,3-dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
   
 0.741
AEB82936.1
TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; KEGG: aav:Aave_4269 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Fumarylacetoacetase, C-terminal-like.
 
  
 0.717
AEB82708.1
TIGRFAM: 2-hydroxymuconic semialdehyde dehydrogenase; KEGG: ajs:Ajs_0220 betaine-aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family.
 
 
 0.716
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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