Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mrdAPenicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (647 aa)    
Predicted Functional Partners:
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.992
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
 
 
 0.985
AEB82750.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.982
AEB84807.1
Peptidoglycan glycosyltransferase; KEGG: ajs:Ajs_2081 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase.
 
 
 0.969
ftsW
Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
 
 0.965
AEB82749.1
KEGG: dia:Dtpsy_0233 rod shape-determining protein MreB; TIGRFAM: Cell shape determining protein MreB/Mrl; PFAM: Cell shape determining protein MreB/Mrl.
 
 
 
 0.963
AEB83211.1
KEGG: dia:Dtpsy_0698 penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase.
 
 
0.952
AEB83640.1
TIGRFAM: Penicillin-binding protein 1C; KEGG: ajs:Ajs_3299 penicillin-binding protein 1C; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; Penicillin-binding, C-terminal.
  
  
 0.942
AEB82777.1
Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: ajs:Ajs_0272 penicillin-binding protein 6; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family.
  
 
 0.940
ftsI
Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
 
  
0.939
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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