Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB82881.1KEGG: dia:Dtpsy_0424 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal; Signal transduction response regulator, receiver domain. (224 aa)    
Predicted Functional Partners:
AEB82880.1
KEGG: dia:Dtpsy_0423 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; HAMP linker domain; GAF; SMART: ATPase-like, ATP-binding domain; HAMP linker domain.
 
 0.996
AEB83400.1
KEGG: ajs:Ajs_3510 multi-sensor signal transduction histidine kinase; PFAM: CHASE3; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain.
 
 
 0.889
AEB86504.1
KEGG: ajs:Ajs_3793 response regulator receiver sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain.
 
 
 0.884
AEB84744.1
KEGG: dia:Dtpsy_1773 putative signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain.
 
 
 0.878
AEB84741.1
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; KEGG: dia:Dtpsy_1737 signal transduction histidine kinase, nitrogen specific, NtrB; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; Signal transduction response regulator, receiver domain.
  
 
 0.529
AEB86480.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; KEGG: rfr:Rfer_2485 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted.
 
 
 0.517
AEB82883.1
KEGG: xtr:100497879 nitrite extrusion protein 1-like; TIGRFAM: Nitrate transporter; PFAM: Major facilitator superfamily MFS-1.
 
   
 0.512
AEB86773.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate cyclase, predicted; PAS fold; GAF; Diguanylate phosphodiesterase, EAL domain; KEGG: bxe:Bxe_C0015 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS; PAC motif; GAF.
 
 
 0.507
AEB82465.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, EAL domain; PAS fold; Diguanylate cyclase, predicted; GAF; KEGG: dia:Dtpsy_0021 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS; PAC motif; GAF.
 
 
 0.505
AEB82879.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
  
 0.484
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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