STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB82932.1Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: dia:Dtpsy_0472 metallophosphoesterase. (252 aa)    
Predicted Functional Partners:
AEB82931.1
PFAM: Serine/threonine-protein kinase-like domain; UspA; KEGG: dia:Dtpsy_0471 serine/threonine protein kinase.
 
   
 0.943
AEB86295.1
Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.809
AEB84570.1
KEGG: maq:Maqu_0130 hypothetical protein.
   
 
 0.720
AEB85533.1
PFAM: Ankyrin repeat; KEGG: dia:Dtpsy_1983 ankyrin.
   
 
 0.720
srkA
Aminoglycoside phosphotransferase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
       0.719
AEB84044.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.564
AEB84904.1
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.505
AEB82933.1
Formyl-CoA transferase; KEGG: ajs:Ajs_0058 L-carnitine dehydratase/bile acid-inducible protein F; PFAM: CoA-transferase family III; Belongs to the CoA-transferase III family.
       0.471
AEB84961.1
PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ajs:Ajs_1963 metal dependent phosphohydrolase.
  
     0.459
AEB82934.1
KEGG: ctt:CtCNB1_2196 hypothetical protein.
       0.410
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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