close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB82936.1TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; KEGG: aav:Aave_4269 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Fumarylacetoacetase, C-terminal-like. (275 aa)    
Predicted Functional Partners:
AEB82935.1
TIGRFAM: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; KEGG: dia:Dtpsy_0475 2-dehydro-3-deoxyglucarate aldolase; PFAM: Aldehyde-lyase domain; Belongs to the HpcH/HpaI aldolase family.
 
 0.996
AEB84094.1
4-hydroxy-2-oxovalerate aldolase; KEGG: aav:Aave_2080 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PFAM: Aldehyde-lyase domain; Belongs to the HpcH/HpaI aldolase family.
 
 0.985
AEB84859.1
KEGG: tjr:TherJR_2256 2-dehydro-3-deoxyglucarate aldolase; PFAM: Aldehyde-lyase domain; Belongs to the HpcH/HpaI aldolase family.
 
 0.975
AEB82711.1
Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.889
AEB82937.1
KEGG: aav:Aave_4268 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: Fumarylacetoacetase, C-terminal-like.
 
  
 0.866
AEB82938.1
PFAM: Amidohydrolase 2; KEGG: aav:Aave_4267 amidohydrolase 2.
 
   
 0.813
AEB82712.1
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
  
 0.745
AEB82939.1
PFAM: Endoribonuclease L-PSP; KEGG: aav:Aave_4266 endoribonuclease L-PSP.
     
 0.732
AEB82940.1
KEGG: aav:Aave_4265 hypothetical protein.
       0.718
AEB83421.1
PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: dia:Dtpsy_2818 5-carboxymethyl-2-hydroxymuconate isomerase.
  
  
 0.652
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.