STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
Coexpression
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[Homology]
Score
AEB83001.1PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; KEGG: dia:Dtpsy_0542 beta-ketoacyl synthase; SMART: Polyketide synthase, beta-ketoacyl synthase domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (405 aa)    
Predicted Functional Partners:
AEB83666.1
TIGRFAM: Malonyl CoA-acyl carrier protein transacylase; KEGG: ajs:Ajs_3279 [acyl-carrier-protein] S-malonyltransferase; PFAM: Acyl transferase.
 0.996
AEB83002.1
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
 
 
 0.992
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.987
AEB85385.1
Enoyl-(acyl-carrier-protein) reductase (NADH); KEGG: dia:Dtpsy_1919 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR.
 
 
 0.979
AEB86720.1
Enoyl-(acyl-carrier-protein) reductase (NADH); KEGG: aav:Aave_2051 enoyl-(acyl carrier protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR.
  
 
 0.976
AEB83667.1
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.957
AEB84223.1
PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: eba:ebA5300 putative dehydrogenase; SMART: Polyketide synthase/Fatty acid synthase, KR.
 
 0.947
AEB86062.1
PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: dia:Dtpsy_2744 short-chain dehydrogenase/reductase SDR.
 
 0.947
AEB83907.1
PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: bbr:BB0613 putative short chain dehydrogenase; SMART: Polyketide synthase/Fatty acid synthase, KR.
 
 0.946
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.942
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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