close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB83070.1KEGG: ajs:Ajs_0616 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: HAD superfamily hydrolase-like, type 3. (273 aa)    
Predicted Functional Partners:
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
       0.837
AEB85611.1
PFAM: Major facilitator superfamily MFS-1; KEGG: dia:Dtpsy_1372 major facilitator superfamily MFS_1.
 
  
 0.692
AEB83069.1
KEGG: dia:Dtpsy_0592 ornithine cyclodeaminase; PFAM: Ornithine cyclodeaminase/mu-crystallin.
     
 0.622
AEB83072.1
PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: rfr:Rfer_0646 short-chain dehydrogenase/reductase SDR.
  
    0.561
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
    0.524
AEB86812.1
PFAM: Nucleotidyl transferase; KEGG: ajs:Ajs_3958 nucleotidyl transferase.
  
  
 0.516
AEB84503.1
PFAM: Protein of unknown function DUF349; KEGG: dia:Dtpsy_2041 hypothetical protein.
 
  
 0.497
AEB83598.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.486
pgi
KEGG: ajs:Ajs_0697 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
  
 0.462
AEB85949.1
KEGG: ppw:PputW619_2172 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; Mannitol dehydrogenase, C-terminal.
  
  
 0.458
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.