Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (541 aa)    
Predicted Functional Partners:
rpmA
TIGRFAM: Ribosomal protein L27; HAMAP: Ribosomal protein L27; KEGG: dia:Dtpsy_0771 50S ribosomal protein L27; PFAM: Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.913
rpmG
KEGG: dia:Dtpsy_2723 50S ribosomal protein L33; TIGRFAM: Ribosomal protein L33; PFAM: Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
   
 
 0.856
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
 
 0.854
AEB83070.1
KEGG: ajs:Ajs_0616 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: HAD superfamily hydrolase-like, type 3.
       0.842
rplL
Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
  
 
 0.840
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
 
 0.835
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.820
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
 
 0.809
rpmF
KEGG: aav:Aave_1181 50S ribosomal protein L32; TIGRFAM: Ribosomal protein L32p; PFAM: Ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family.
   
   0.807
rplQ
TIGRFAM: Ribosomal protein L17; HAMAP: Ribosomal protein L17; KEGG: dia:Dtpsy_0399 50S ribosomal protein L17; PFAM: Ribosomal protein L17.
  
   0.807
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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