Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEB83072.1PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: rfr:Rfer_0646 short-chain dehydrogenase/reductase SDR. (256 aa)    
Predicted Functional Partners:
AEB82515.1
KEGG: vap:Vapar_0736 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR.
 
  
 0.741
AEB86369.1
KEGG: bbr:BB4035 putative oxidoreductase; PFAM: Short-chain dehydrogenase/reductase SDR.
 
  
 0.738
AEB86251.1
KEGG: aav:Aave_3940 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR.
 
  
 0.730
AEB83877.1
PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: bbr:BB0604 short chain dehydrogenase.
 
   
 0.709
AEB82572.1
2,4-dienoyl-CoA reductase (NADPH); KEGG: ajs:Ajs_0109 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR.
 
  
 0.608
AEB83070.1
KEGG: ajs:Ajs_0616 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: HAD superfamily hydrolase-like, type 3.
  
    0.567
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
       0.547
AEB86840.1
KEGG: ajs:Ajs_3977 3-ketoacyl-(acyl-carrier-protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR.
 
  
 0.476
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
       0.461
AEB83069.1
KEGG: dia:Dtpsy_0592 ornithine cyclodeaminase; PFAM: Ornithine cyclodeaminase/mu-crystallin.
       0.415
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (34%) [HD]